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GLP-1s Are Not Just for Weight Loss Anymore

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And honestly, that's the part nobody's really talking about. We're going to dive into GLP-1s, but not the way you've been hearing about them. We're going beyond weight loss. Because saying GLP-1s are just for weight loss is kind of like saying a smartphone is just for making phone calls. It really has so many things that it signals on a regular basis. In the podcast, I briefly mentioned the SELECT Trial, but I want to slow down for a moment and give you a little more context because this study truly changed the conversation around GLP-1 medications. In 2023, the SELECT Trial (published in the New England Journal of Medicine https://www.nejm.org/doi/full/10.1056/NEJMoa2307563 ) followed more than 17,000 adults who were overweight or obese and had established cardiovascular disease, but importantly, they did not have diabetes. Participants were given semaglutide at the 2.4 mg dose (the dose used for weight management) and were followed for several years. What researc...

Why the FDA (Food and Drug Administration) Finally Removed the Blackbox Warning on Estradiol

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  After 20+ Years, the FDA Finally Admitted What We've Known All Along This is huge. For over two decades, estrogen carried a black box warning—the FDA's strongest safety warning—that scared women away from treatment. It shaped medical practice across the country. It created widespread fear. It kept millions of women suffering unnecessarily. And the truth is, this fear was based on flawed data all along. The FDA finally removed the black box warning on estradiol in 2024. And it's one of the most important shifts in women's health in a generation. Let's talk about why this finally happened, what it means for women right now, and why it took so damn long. The WHI Study Never Deserved a Black Box Warning in the First Place The entire reason estrogen was labeled dangerous comes back to one study: the Women's Health Initiative (WHI) from 2002. And that study was fundamentally flawed from the beginning. "The Women's Health Initiative study was flawed." L...

The Real Benefits of Estradiol and Progesterone: What Women Were Never Told

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  Twenty Years of Fear. Zero Discussion of Benefits. For over 20 years, women were terrified away from hormone therapy because of a study that never reflected real menopausal patients. And because of that fear, women missed out on benefits that could have dramatically improved their quality of life. Estradiol (E2-the workhorse type of estrogen) and progesterone are not the villains they were made out to be. In reality, the benefits are powerful, protective, and life-changing when used correctly. Women were told about risks—real or imagined—but never about benefits. That's not informed consent. That's fear-based medicine. And it needs to end. This is what women should have been told from the beginning. Women Lost Decades of Health Because of Fear, Not Facts Women were taken off estrogen for the wrong reasons. Doctors were scared to prescribe. Patients were scared to ask. The media amplified fear without context. And the fallout was enormous. "We have this whole generation o...