GLP-1s Are Not Just for Weight Loss Anymore
And honestly, that's the part nobody's really talking about. We're going to dive into GLP-1s, but not the way you've been hearing about them. We're going beyond weight loss. Because saying GLP-1s are just for weight loss is kind of like saying a smartphone is just for making phone calls. It really has so many things that it signals on a regular basis. In the podcast, I briefly mentioned the SELECT Trial, but I want to slow down for a moment and give you a little more context because this study truly changed the conversation around GLP-1 medications. In 2023, the SELECT Trial (published in the New England Journal of Medicine https://www.nejm.org/doi/full/10.1056/NEJMoa2307563 ) followed more than 17,000 adults who were overweight or obese and had established cardiovascular disease, but importantly, they did not have diabetes. Participants were given semaglutide at the 2.4 mg dose (the dose used for weight management) and were followed for several years. What researc...